|
KMID : 0043320050280111219
|
|
Archives of Pharmacal Research
2005 Volume.28 No. 11 p.1219 ~ p.1223
|
|
|
Synthesis of 6-[2-(Benzoxazol-2-ylmethylamino )ethoxy]-1-Alkyl1 H-lndole-2-Carboxylic Acid and Inhibitory Activity on -Amyloid Aggregation
|
|
Lee Sun-Mi
Jeon Raok
|
|
|
Abstract
|
|
|
|
6-[2-(Benzoxazol-2-ylmethylamino)ethoxy]-1-alkyl-1H-indole-2-carboxylic acids were designed and synthesized as -amyloid (A) fibril assembly inhibitors. Their inhibitory activity on A, aggregation was evaluated by thioflavin T assay although their activities were insignificant.
|
|
|
KEYWORD
|
|
|
Indole, Alzheimer’s disease
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|